The presenters will share the case of a critically ill, anephric, preterm infant from birth to 12 months. This case will provide education on different modalities of renal replacement therapy, including Carpediem™, aquapheresis, hemodialysis, and peritoneal dialysis, which the infant in this case went through. This case will report nutrition challenges starting in the NICU and through all the transition phases, including the outpatient nephrology clinic. In addition, information about the nutrition challenges associated with infantile end-stage kidney disease will be reviewed. These challenges include but are not limited to growth impairment, nutritional deficiencies, feeding difficulties, altered bone mineral metabolism, and electrolyte abnormalities.